MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA Type-c) is a 16-amino acid regulatory peptide encoded within the mitochondrial 12S ribosomal RNA locus. It acts as a retrograde signaling molecule translocating to the nucleus under metabolic stress. It is supplied strictly for in vitro AMPK (AMP-activated protein kinase) phosphorylation kinetics, folate cycle and de novo purine biosynthesis inhibition studies, GLUT4 expression and glucose utilization assays, and laboratory mitochondrial bioenergetics research models. Supplied as a stable lyophilized powder suitable for analytical reconstitution.

Technical Specifications

• Chemical Name / Synonym: MOTS-c / Mitochondrial-Derived Peptide MOTS-c / H-Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg-OH

• Molecular Formula: C101H152N28O22S2

• Molecular Weight: 2174.62 g/mol

• Physical Form: Lyophilized solid / cake

• Purity Grade: ≥ 98.0% (analytical verification via HPLC-MS)

• Storage Conditions: Store sealed at -20°C in a dry environment protected from light. Keep desiccated until experimental reconstitution.

Analytical Quality & Testing Every production batch undergoes analytical screening via HPLC and Mass Spectrometry to confirm chemical identity, sequence fidelity, and purity standards. Batch-specific Certificates of Analysis (CoA) and analytical testing records are maintained on file and available to qualified laboratories upon request.

LABORATORY RESEARCH USE ONLY This biochemical reagent is manufactured and distributed strictly for in vitro laboratory experimentation, diagnostic assay development, and analytical testing. It is not a drug, dietary supplement, therapeutic agent, cosmetic, or food product. Not for human, animal, or clinical administration, consumption, injection, or veterinary application. Must be handled exclusively by qualified personnel adhering to standard chemical laboratory safety protocols.