Kisspeptin-10 is a synthetic 10-amino acid amidated peptide corresponding to the C-terminal core sequence (residues 45–54) of human metastin / kisspeptin-54 (encoded by the KISS1 gene). As the minimal sequence required for full biological affinity, it functions as a potent endogenous agonist of the G-protein coupled receptor GPR54 (KISS1R / AXOR12). It is supplied strictly for in vitro KISS1R affinity and selectivity profiling, Gαq/11-mediated phospholipase C activation and intracellular calcium mobilization kinetics, GnRH release signaling dynamics, and laboratory metastasis-suppressor pathway research models. Supplied as a stable lyophilized powder suitable for analytical reconstitution.

Technical Specifications

• Chemical Name / Synonym: Kisspeptin-10 / Metastin (45-54) amide / KISS1 (112-121) / H-Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2

• Molecular Formula: C63H83N17O14

• Molecular Weight: 1302.44 g/mol

• Physical Form: Lyophilized solid / cake

• Purity Grade: ≥ 98.0% (analytical verification via HPLC-MS)

• Storage Conditions: Store sealed at -20°C in a dry environment protected from light. Keep desiccated until experimental reconstitution.

Analytical Quality & Testing Every production batch undergoes analytical screening via HPLC and Mass Spectrometry to confirm chemical identity, sequence fidelity, and purity standards. Batch-specific Certificates of Analysis (CoA) and analytical testing records are maintained on file and available to qualified laboratories upon request.

LABORATORY RESEARCH USE ONLY This biochemical reagent is manufactured and distributed strictly for in vitro laboratory experimentation, diagnostic assay development, and analytical testing. It is not a drug, dietary supplement, therapeutic agent, cosmetic, or food product. Not for human, animal, or clinical administration, consumption, injection, or veterinary application. Must be handled exclusively by qualified personnel adhering to standard chemical laboratory safety protocols.